CANTAB Research Grant assists research into defining cognitive phenotypes in individuals with CNVs a

Ciara Molloy recently spoke to us about the impact that receiving one of the three 2020 CANTAB Research Grant prizes will have on her research: ‘The impact of rare copy number variants on cognition: Defining cognitive phenotypes in individuals with CNVs associated with neurodevelopmental and neuropsychiatric disorders.’

2020 CANTAB Research Grant supports research into combined dexmedetomidine / ketamine nasal spray fo

The winner of one of the three 2020 CANTAB Research Grant prizes, Dr Amie Hayley, Swinburne University of Technology explains the impact CANTAB will have on her research: Combined dexmedetomidine/ketamine nasal spray for analgesia: a pilot feasibility and efficacy trial.

CANTAB Research Grant funds new ways to assess vascular cognitive impairment and dementia (VCID) in

Dr Simone De Luca recently received the 2020 CANTAB Research Grant primary award for her project: “New ways to assess vascular cognitive impairment and dementia (VCID) in chronic lung disease”. We spoke to her about the impact winning would have on her research.

Using CANTAB to study the relationships between executive function, eating behavior and preoperative

PhD candidate Gro Walø-Syversen of Oslo University Hospital, shared the role that CANTAB played in her latest publication: Executive Function, Eating Behavior, and Preoperative Weight Loss in Bariatric Surgery Candidates: An Observational Study

Does the impact of high-altitude impair cognitive performance?

Alexander Friend shares the role CANTAB played in the research he conducted on cognitive impairment at high-altitude while at The University of Birmingham.

Successful delivery of CANTAB cognitive assessments across diverse health systems

At the virtual AAIC 2020 conference Dr Elizabeth Baker presented data on the successful delivery of CANTABTM assessments across diverse health systems and ages: 10 – 90 years old.

The study captures normative performance across the lifespan to support a cognitive screening tool for characterising a range of neuropsychological disorders in clinics across India.

Guidance for including elderly patients in clinical trials

Older adults shoulder a disproportionate burden of chronic diseases and consumption of prescription drugs. Nevertheless, older adults, especially those aged over 75 years, are chronically under-represented in clinical trials. In this two part series, Dr Kiri Granger explores the risks of under-presentation and outlines guidance for including older adults in clinical trials.

Read on for session two: key design considerations when including elderly patients in clinical trials, with a focus on cognitive assessment.  

Why are elderly patients under-represented in clinical trials?

Older adults are consistently under-represented in clinical trials, even though they take more prescription medications than any other group. In this two part series, Dr Kiri Granger will explore this under-presentation and outline practical considerations for including older adults in clinical trials.

Read on for session one: the importance of addressing the evidence-practice gap.  

Does long-term poor sleep contribute to the development of Alzheimer’s disease?

We caught up with Jana Thomas of Radboud University Medical Centre to find out more about the bidirectional relationship between poor sleep and Alzheimer’s disease.

Remote cognitive testing: what are the scientific and operational considerations?

Remote testing solutions for clinical trials and academic research are increasingly being adopted resulting in time and cost savings for clinical research studies and reduced participation burden for study patients. However, not every study is suitable for this medium. In this article we cover the scientific and operational factors for deciding whether to use remote cognitive testing in an upcoming trial. 

CANTAB Research Grant 2020 - Results

The results of the 2020 CANTAB Research Grant are in! Once again we were overwhelmed by the quality of applications we received – which made it a tough job for our judging panel to narrow the research proposals down.

Examination of the neural basis of psychotic-like experiences in adolescence during processing of em

We caught up with Dr Evan Papanastasiou from King's College London to find out why he chose CANTAB to examine the neural basis of psychotic-like experiences in adolescence during processing of emotional faces.

What are the biological mechanisms behind chemotherapy-associated cognitive impairment?

Despite chemotherapy-associated cognitive impairment (CACI, aka chemobrain) affecting 75% of all cancer survivors, little is understood about the mechanisms underlying the disorder. In efforts to address this research gap, Prof Alexandre Chan from the University of California, Irvine used CANTAB to conduct an evaluation of DNA Methyltransferase 1 (DNMT1) Single Nucleotide Polymorphisms and Chemotherapy-Associated Cognitive Impairment. Read on to find out the results.  

How does an alcohol hangover affect cognition?

We caught up with Lydia Devenney from Letterkenny Institute of Technology to find out why she chose CANTAB to assist her research into investigating attention, memory functioning, and mood in a natural setting with real‐life alcohol consumption levels.

Modelling associations between neurocognition and functional course in young people with emerging

We caught up with Jacob Crouse from the University of Sydney’s Brain and Mind Centre to discuss his research into key factors that underpin mental health disorders in young people, with a view to improving outcomes. 

Why does PSYSCAN use CANTAB?

PSYSCAN is a global project, which aims to develop a neuroimaging-based tool that will help healthcare professionals to address key clinical issues for patients with psychotic disorders. We caught up with study coordinator – Aimée Westerveld – to find out more about the role of CANTAB in the project. 

What is the impact of stress and environment on executive function and motivation for primary school

We caught up with Toby Bartle, Registered Psychologist and PhD Candidate at James Cook University, to find out why he chose CANTAB when looking at the impact of stress and environment on executive function and motivation for primary school children.

What is the impact of hydration status and exercise on cognitive performance?

We caught up with University of Ulster researcher, Kyle Wallace, to find out why he chose CANTAB to investigate the links between cognitive function, hydration status and martial arts. 

Cambridge Cognition signs new eCOA contracts

Cambridge Cognition today announced it has won a significant new phase IV clinical trial contract for use of its electronic clinical outcomes assessment (eCOA) platform, CANTAB Connect.

Why is it important to assess cognition in criminal cases?

Dr Seán Haldane is a Consultant Neuropsychologist and expert witness who provides reports for defence lawyers, the Crown Prosecution Service and the police. We caught up with Dr Haldane to discuss how CANTAB Insight is integral to his work.  

CANTAB for cognitive screening in a young adult mental health unit

Mental health researcher at the University of Sydney: Brain and Mind Centre, Ashleigh Tickell, recently submitted her PhD on the feasibility of cognitive screening as standard clinical care in a young adult mental health unit. We caught up with Ashleigh to find out the outcomes of using CANTAB for her project.

CANTAB Research Grant funds investigation of chronic inflammation in depression

PhD Student Naoise Mac Giollabhui received a CANTAB Research Grant in 2018 for his project: ‘Chronic inflammation as a pathway to cognitive dysfunction in adolescents and young adults with a history of elevated depressive symptoms’. We caught up with Naoise to discuss how the grant will benefit his research. 

A solution for improving recruitment into early Alzheimer’s disease clinical trials

Screening patients into early stage Alzheimer’s trials can be costly and time-consuming. Kenton Zavitz, PhD, Director of Clinical Affairs proposes a potential solution for improving recruitment into clinical trials. 

Cambridge Cognition announces major contract win and funding award

We're pleased to announce the award of a major new pharmaceutical clinical trial contract and a Digital Health Catalyst grant from Innovate UK.

Pen-and-paper vs. computerised testing: which method do older adults prefer?

Exciting new research shows not only that web-based cognitive assessments are suitable for older adults but, for many, computerised assessments are actually preferable to traditional pen-and-paper tasks. 

Hogrefe becomes exclusive distributor of CANTAB in Finland

We’re pleased to announce that Hogrefe Psykologien Kustannus Oy is now an exclusive distributor of CANTAB software products for use in Finland by academic researchers and healthcare professionals.

Home-based computerised testing: a valid alternative to in-person cognitive assessments?

A comparison of in-person and web-based computerised cognitive testing with CANTAB.

Pre-Screening for Episodic Memory Deficits To Enrich Recruitment in Alzheimer's Disease Trials

Identifying participants in the ‘pre-clinical’ or ‘prodromal’ stage of Alzheimer's disease prior to the onset of cognitive and functional decline can be challenging, time-consuming and expensive. Can, pre-screening for episodic memory deficits enrich the recruitment of eligible participants in early Alzheimer’s disease clinical trials?

Paired Associates Learning: Adding Sensitivity By Measuring Reaction Times

Computerised testing brings an unprecedented ability to capture more detailed information about patient responses. This could provide novel insights into cognitive processes, and greater discriminatory power in predicting cognitive deficits and decline in Alzheimer's and other diseases.

Results from CANTAB in the Deep and Frequent Phenotyping Feasibility Study

Dr Rosemary Abbott presented this poster at the Dementias Platform UK Annual Scientific Meeting on 4th May 2017.