COVID-19 Cognitive Assessment Battery

To understand the impact of COVID-19 on cognitive function, researchers must use sensitive and reliable cognitive assessments which target appropriate domains. In this article Operational Scientist, Iona Pickett, discusses the challenges of designing a cognitive testing battery for use in those recovering from COVID-19 and describes our recommended CANTAB battery for COVID-19 studies.

Understanding the challenges of assessing cognitive function in patients recovering from COVID-19

While several initiatives have begun investigating the neuropsychological effects of COVID-19, the nature and causes of cognitive impairment found in COVID-19 survivors are not yet fully understood. In this article Operational Scientist, Iona Pickett, discusses the challenges faced by researchers assessing cognition in those recovering from COVID-19.

CANTAB Research Grant assists research into structural and functional changes in memory

We caught up with Julius Rave to talk about the impact that the primary 2021 CANTAB Research Grant prize will have on his research: Exploring structural and functional changes in memory-associated networks in patients expressing cognitive deficits after a COVID-19 infection.

Research into the cognitive impact of COVID-19 on patients with and without sleep complaints

Pim Heckman speaks to us about the impact that receiving one of the three 2021 CANTAB Research Grant prizes will have on his research into clearing COVID-19 cognitive brain fog

Cognitive assessment of COVID-19 patients following mechanical ventilation

Jamileth More recently spoke to us about the impact that receiving one of the three 2021 CANTAB Research Grant prizes will have on her research into monitoring protocol of COVID-19 patients survivors of mechanical ventilation.

CANTAB used to assist with identifying patients with mild cognitive impairment and subjective cognit

Dr. Andrea McGrattan, a Research Dietitian and Lecturer in Nutrition and Dietetics, spoke to us about her PhD research at Queen’s University Belfast, using CANTAB cognitive testing within a Mediterranean Diet feasibility study, “THINK-MED”, among people with cognitive impairment.  

New study uses CANTAB to differentiate typical and pathological ageing

Find out more about how María Campos Magdaleno, PhD of Universidade de Santiago de Compostela is using CANTAB to investigate cognitive changes in typical and pathological ageing.

Cognition and COVID-19: CANTAB Research Grant - Results

The results of the 2021 CANTAB Research Grant are in! This year's award was focussed on the connection between cognition and COVID-19. 

CANTAB and CENTRE-TBI – 10 years working together

CENTRE-TBI recently concluded their 10 year study into the relationship between cognition and function in daily life after traumatic brain injury. We caught up with Prof Lindsay Wilson to hear the key findings from this worldwide study. 

Engagement and Adherence to Remote Testing in Middle-Aged Adults at Risk of Dementia

At the virtual ADPD 2021 event, Emily Thorp discussed engagement and adherence to remote testing in middle-aged adults at risk of dementia.

Experiences of Fatigue in Chronic Disease: Effects on Mental Health

At the recent Chronic Disease & Mental Health virtual event, Iona Pickett discussed experiences of fatigue in chronic disease: effects on mental health. 

Using CANTAB to investigate specific contributions from the volume of hippocampal subregions to visu

We recently caught up with Tamara Shavitt, a psychology student who conducted research at the Faculty of Medicine, University of São Paulo to discuss how CANTAB impacted her research: investigate specific contributions from the volume of hippocampal subregions to visuospatial memory tasks.

New study finds CANTAB is sensitive to very early cognitive changes in premanifest Huntington’s dise

Dr. Christelle Langley, postdoctoral Research Associate at the University of Cambridge School of Clinical Medicine shared the role that CANTAB played in her latest publication: Fronto-striatal circuits for cognitive flexibility in far from onset Huntington’s Disease: Evidence from the Young Adult Study

What is the association between anabolic androgenic steroid dependence and executive dysfunction?

We recently spoke with Dr Lisa Evju Hauger to discuss the impact CANTAB had on her research into exploring executive function in relation to long-term anabolic androgenic steroids (AAS) use and dependence.

Bringing home cognitive assessment: Comparing web-based and in-person CANTAB

In times of a pandemic, being able to deliver cognitive tests remotely becomes even more relevant and can prevent the interruption of clinical studies: but are cognitive assessments comparable in the clinic and the home? New research, published in the Journal of Medical Internet Research, demonstrates that performance on the Cambridge Neuropsychological Test Automated Battery (CANTABTM) is broadly comparable when delivered unsupervised online or in-person in the laboratory.

Using CANTAB to examine the potential synergistic effects of a combination of omega-3 fatty acids, c

Dr Rebecca Power, Postdoctoral Researcher at the Nutrition Research Centre Ireland, shared the role that CANTAB played in her latest publication: Targeted Nutritional Intervention for Patients with Mild Cognitive Impairment: The Cognitive impAiRmEnt Study (CARES) Trial 1

Automated administration of Serial Subtraction in a remote data collection context: novel timing fea

New research presented at CTAD 2020 reports the successful derivation of novel measures of timing for a more nuanced assessment of performance on the Serial Subtraction task. 

Unlocking cognitive research during lockdown: post-webinar Q and A

The volume of discussion and questions during our recent webinar: Remote Cognitive Testing and Lessons Learned During Lockdown was great to see. Unfortunately we were unable to answer all the questions in the time we had so Dr Caroline Skirrow has put together a Q and A addressing some of the key themes raised.  

CANTAB Research Grant assists research into defining cognitive phenotypes

Ciara Molloy recently spoke to us about the impact that receiving one of the three 2020 CANTAB Research Grant prizes will have on her research: ‘The impact of rare copy number variants on cognition: Defining cognitive phenotypes in individuals with CNVs associated with neurodevelopmental and neuropsychiatric disorders.’

2020 CANTAB Research Grant supports research into combined dexmedetomidine / ketamine nasal spray fo

The winner of one of the three 2020 CANTAB Research Grant prizes, Dr Amie Hayley, Swinburne University of Technology explains the impact CANTAB will have on her research: Combined dexmedetomidine/ketamine nasal spray for analgesia: a pilot feasibility and efficacy trial.

CANTAB Research Grant funds new ways to assess vascular cognitive impairment and dementia (VCID) in

Dr Simone De Luca recently received the 2020 CANTAB Research Grant primary award for her project: “New ways to assess vascular cognitive impairment and dementia (VCID) in chronic lung disease”. We spoke to her about the impact winning would have on her research.

Using CANTAB to study the relationships between executive function, eating behavior and preoperative

PhD candidate Gro Walø-Syversen of Oslo University Hospital, shared the role that CANTAB played in her latest publication: Executive Function, Eating Behavior, and Preoperative Weight Loss in Bariatric Surgery Candidates: An Observational Study

Does the impact of high-altitude impair cognitive performance?

Alexander Friend shares the role CANTAB played in the research he conducted on cognitive impairment at high-altitude while at The University of Birmingham.

Successful delivery of CANTAB cognitive assessments across diverse health systems

At the virtual AAIC 2020 conference Dr Elizabeth Baker presented data on the successful delivery of CANTABTM assessments across diverse health systems and ages: 10 – 90 years old.

The study captures normative performance across the lifespan to support a cognitive screening tool for characterising a range of neuropsychological disorders in clinics across India.

Guidance for including elderly patients in clinical trials

Older adults shoulder a disproportionate burden of chronic diseases and consumption of prescription drugs. Nevertheless, older adults, especially those aged over 75 years, are chronically under-represented in clinical trials. In this two part series, Dr Kiri Granger explores the risks of under-presentation and outlines guidance for including older adults in clinical trials.

Read on for session two: key design considerations when including elderly patients in clinical trials, with a focus on cognitive assessment.  

Why are elderly patients under-represented in clinical trials?

Older adults are consistently under-represented in clinical trials, even though they take more prescription medications than any other group. In this two part series, Dr Kiri Granger will explore this under-presentation and outline practical considerations for including older adults in clinical trials.

Read on for session one: the importance of addressing the evidence-practice gap.  

Does long-term poor sleep contribute to the development of Alzheimer’s disease?

We caught up with Jana Thomas of Radboud University Medical Centre to find out more about the bidirectional relationship between poor sleep and Alzheimer’s disease.

Remote cognitive testing: what are the scientific and operational considerations?

Remote testing solutions for clinical trials and academic research are increasingly being adopted resulting in time and cost savings for clinical research studies and reduced participation burden for study patients. However, not every study is suitable for this medium. In this article we cover the scientific and operational factors for deciding whether to use remote cognitive testing in an upcoming trial. 

CANTAB Research Grant 2020 - Results

The results of the 2020 CANTAB Research Grant are in! Once again we were overwhelmed by the quality of applications we received – which made it a tough job for our judging panel to narrow the research proposals down.

Examination of the neural basis of psychotic-like experiences in adolescence during processing of em

We caught up with Dr Evan Papanastasiou from King's College London to find out why he chose CANTAB to examine the neural basis of psychotic-like experiences in adolescence during processing of emotional faces.